Neonatal hypoxic-ischemic encephalopathy diagnosis and treatment: a National Survey in China
نویسندگان
چکیده
Abstract Background Neonatal hypoxic-ischemic encephalopathy (HIE) affects as many 100,000 infants each year in China. Therapeutic hypothermia reduces HIE related mortality and long-term neurodevelopmental disabilities. National guidelines for management were published a decade ago. This study aimed to investigate the current status of diagnosis treatment Method prospective cross-sectional national survey used questionnaire evaluating practices management. Descriptive statistics Chi-square or Fisher’s exact test used, p -value < 0.05 was considered significant. Results The 273 hospitals that completed located 31 34 provincial districts Eighty-eight percent Level III hospitals, 74% treated 10 more cases annually. Awareness rates diagnosis, treatment, therapeutic protocol 85, 63, 78%, respectively. Neurological manifestations blood gas diagnostic criteria by 96% (263/273) 68% (186/273) 54% (147/273) hospitals. percentage general implemented (43%, 71/165) significantly lower than maternity infant (67%, 49/73) ( χ 2 = 11.752, 0.001) children’s (77%, 27/35) 13.446, 0.001). Reasons not providing included reduction recent years (39%), high cost cooling devices (31%), lack training (26%), safety concerns (4%). Among provided hypothermia, 27% (39/147) full compliance with recommended protocol. Eighty-one (222/273) putative neuroprotective agents alone combination cooling. Ninety-one had follow-up programs HIE. Conclusions There is significant heterogeneity has become standard care neonatal nationwide. Unproven are widely treatment. Nationwide standardization dissemination represent opportunities reduce improve outcomes children affected
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ژورنال
عنوان ژورنال: BMC Pediatrics
سال: 2021
ISSN: ['1471-2431']
DOI: https://doi.org/10.1186/s12887-021-02737-6